Investigation of PJ vs. Sugar on Glucose Levels in Healthy and Prediabetic Subjects

Inclusion Criteria: 1. Age 20-50 years and any racial/ethnic group 2. Typically consume low fiber/polyphenol diet (beige diet) 3. Healthy, normal weight individuals with a BMI of \>18 to 26.9 kg/ m2 with fasting serum glucose \<100mg/dL or A1c \<5.7 4. Prediabetic, obese individuals with a BMI of \>27 kg/ m2 and fasting serum glucose \>100, but \<126 mg/dL or A1c \>5.7% but \< 6.4%\] 5. Subjects must read and sign the informed consent prior to participation 6. Subjects must be in generally good health 7. Subjects must be able and willing to comply with the requirements of the protocol. Exclusion Criteria: 1. Eating a high fiber/polyphenol diet or taking any medication or dietary supplements that interfere with the absorption of polyphenols. 2. History of gastrointestinal surgery, diabetes mellitus on medications, or other serious medical condition, such as chronic hepatic or renal disease, bleeding disorder, congestive heart disease, chronic diarrhea disorders, myocardial infarction, coronary artery bypass graft, angioplasty within 6 months prior to screening, current diagnosis of uncontrolled hypertension (defined as systolic BP \>160mmHg, diastolic BP \> 95mmHg), active or chronic gastrointestinal disorders, bulimia, anorexia, laxative abuse, or endocrine diseases (except thyroid disease requiring medication) as indicated by medical history 3. Any subject currently taking blood thinning medications such as Warfarin or Coumadin 4. Currently uses tobacco products. 5. Currently has an alcohol intake \> 20 g ⁄ day; 6. Currently has a coffee intake \> 3 cups ⁄ day; 7. Screening laboratory value outside of the laboratory normal range that is considered clinically significant for study participation by the investigator. 8. Using prebiotics, probiotics, yogurt, and/or any fiber supplements regularly 9. Allergy or sensitivity to pomegranate. Subjects will be excluded if there is a prior history of such sensitivity. Since these foods are commonly eaten and allergies are rare, subjects should be aware of this sensitivity prior to entering the study. In addition, any subject with a history of allergy or anaphylaxis of any kind will be excluded 10. Taking antibiotics or laxatives within the past 3 months 11. Is unable or unwilling to comply with the study protocol.