This study examines the effect of soluble fiber dextrin on food intake, appetite, and physiological markers of appetite. Adults aged 18-45 years with a BMI were recruited for this study. Participants were given two doses of SFD in the morning and appetite, food intake and physiological markers of appetite were measured over 10 years.
Overweight and obesity are leading health problems. The study investigates the effect of a food ingredient from two different sources at two different doses on food intake and appetite markers over a 10 hour period. All participants reported to the laboratory first thing in the morning and remained in the laboratory until after their evening meal. A fixed breakfast was served but the participants were free to eat as much as they liked at lunch and dinner. Blood was taken at regular intervals during the day and assayed for glucose and several hormones related to appetite. Subjective measures of appetite were also collected over the 10 hour test session.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
50
Ingredient based on resistant starch
Food intake
Food intake measured at lunch and evening meal.
Time frame: 10 hours
Appetite
Subjective appetite measures using questionnaires at regular intervals over 10 hours,
Time frame: 10 hours
CCK
Plasma CCK measured at regular intervals over 10 hours.
Time frame: 10 hours
GLP-1
Plasma GLP-1 measured at regular intervals over 10 hours.
Time frame: 10 hours
PYY3-36
Plasma PYY3-36 measured at regular intervals over 10 hours.
Time frame: 10 hours
Breath Hydrogen
Breath hydrogen measured at regular intervals over 10 hours.
Time frame: 10 hours
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