The goal of this study is to examine in vivo thrombosis characteristics with ultrasound shear wave elastography (SWE) and determine the relationship with thrombus resolution and postthrombotic syndrome (PTS) in patients with acute proximal Deep Vein Thrombosis (DVT).
Study Type
OBSERVATIONAL
Enrollment
35
Mayo Clinic
Rochester, Minnesota, United States
Thrombus Resolution
Ultrasound images of lower extremity DVTs comparing the initial diagnostic image of thrombus to a subsequent study performed after 3 months of anticoagulation.The lower extremity venous system is divided into 12 segments. Each vein segment will be analyzed on initial ultrasound and recorded 0 (no DVT), 1 (non-occlusive DVT), or 2 (occlusive DVT). The follow up ultrasound will be analyzed per vein segment and recorded as no residual thrombus, minimal chronic post-thrombotic changes, \> 50% resolution, \< 50% resolution, near occlusive DVT, no change, and progressive DVT.
Time frame: 3 Months after diagnosis of DVT.
Post-thrombotic syndrome
Measured using the Villalta Score. Scale 0-33 with higher values indicating more severe symptoms.
Time frame: 6 months after diagnosis of DVT
Vein Specific Quality of Life
Measured using The Venous Insufficiency Epidemiological and Economic Study (VEINES) QOL survey. Scores range from 0-100 with higher scores indicating better quality of life.
Time frame: 6 months after diagnosis of DVT
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