NCT04597814 - The Relationship Between the Tumor Markers and Interstitial Lung Disease | Crick

Overview

The serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 are often increased in interstitial lung disease patients. This study was undertaken to investigate the source of these serum tumor markers.

The serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 are often increased in interstitial lung disease patients. This study was undertaken to investigate the source of these serum tumor markers.We hypothesis that these tumor markers are released from the lung. The broncholveolr lvge fluid levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 were measured in the interstitial lung disease patients before lung transplantation. The immunohistochemical test was performed in the specimen lung after lung transplantation.

Study Type

OBSERVATIONAL

Enrollment

13

Conditions

the Relationship Between the Tumor Markers and Interstitial Lung Disease Patients

Interventions

No InterventionOTHER

No Intervention

Eligibility

Sex: ALLMin age: 20 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria 1.Interstitial lung disease patients for lung transplantation \- Exclusion Criteria: 1. tumor 2. Interstitial lung disease patients could not be performed by lung transplantation

Locations (1)

The First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China

Outcomes

Primary Outcomes

serum levels of carcinoembryonic antigen (CEA)

Time frame: 6months

serum levels of carbohydrate antigen 19-9 (CA19-9)

Time frame: 6months

serum levels of carbohydrate antigen 125(CA125)

Time frame: 6months

The alveolar lavage fluid levels of carcinoembryonic antigen (CEA)

Time frame: 1 week

The alveolar lavage fluid levels of carbohydrate antigen 19-9 (CA19-9)

Time frame: 1 week

The alveolar lavage fluid levels of carbohydrate antigen 125

Time frame: 1 week

The lung tissue levels of carcinoembryonic antigen (CEA)

Time frame: 1 week

The lung tissue levels of carbohydrate antigen 19-9 (CA19-9)

Time frame: 1 week

The lung tissue levels of carbohydrate antigen 125