The aim of this investigation was to assess safety and efficacy of allogenic NK cells therapy for refractory MDS-EB.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
10
10 patients with refractory MDS-RAEB were treated with allogeneic NK cell regimen. Allogeneic NK cell regimen ×3 cycle; Cyclophosphamide 300mg/m2.d d1to 3; G-CSF 150ug bid d4-11; Azacitidine 75mg/m2 d5-11; Allogeneic NK cell 10-30×10\^6/kg d13,d15 .
The 2nd Hospital of Shandong University
Jinan, Shandong, China
Objective Response Rate (ORR) (PR+CR)
The proportion of patients with complete response(CR) or partial response(PR) as measured by International Working Group efficacy Criteria for myelodysplastic syndromes
Time frame: 3 months
Overall survival(OS)
The proportion of patients with overall survival(OS).
Time frame: 1 year
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.