OCTA Study: Retinal Vascular Changes in Patients With SARS-CoV-2 Infection

Federico II University40 enrolled

Overview

This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that have been affected by COVID-19.

To investigate the potential role of optical coherence tomography angiography in identifying the changes in retinal vessel density in patients that have been affected by COVID-19. The optical coherence tomography angiography represents a noninvasive diagnostic technique that allows a detailed analysis of retinal vascular features.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Covid19

Interventions

Optical coherence tomography angiographyDIAGNOSTIC_TEST

Each subject underwent optical coherence tomography angiography to evaluate the retinal vessel density.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * age older than 18 years * diagnosis of previous COVID-19 * absence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases. * absence of significant lens opacities, low-quality OCT and OCT-A images. Exclusion Criteria: * age younger than 18 years * absence of previous diagnosis of COVID-19 * presence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases. * presence of significant lens opacities, low-quality OCT and OCT-A images.

Locations (1)

University of Naples "Federico II"

Naples, Italy

Outcomes

Primary Outcomes

The measurements of retinal features in patients with previous diagnosis of COVID19, using optical coherence tomography angiography.

The parameter analyzed by optical coherence tomography angiography was: retinal vessel density

Time frame: one month

Data from ClinicalTrials.gov

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