Early Detection of COVID-19 Using Breath Analysis

Scentech Medical Technologies Ltd50 enrolled

Overview

EARLY DETECTION OF COVID-19 USING BREATH ANALYSIS- FIRST CROSS-SECTIONAL STUDY

Primary objective- to identify and evaluate a set of biomarkers that represent both the genetic expression of the virus itself (SARS-CoV-2) and the metabolic activity of the immune system's response to the virus.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Covid19

Interventions

Breath biopsy sampling using the ReCIVA Breath SamplerDIAGNOSTIC_TEST

Breath biopsy sampling using the ReCIVA Breath Sampler

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18 to 55 years at the time of consent * Positive results for SARS-CoV-2 * Capable of understanding written and/or spoken language * Able to provide informed consent Exclusion Criteria: * Age under 18 years old * (Anticipated) inability to complete breath sampling procedure due to e.g. hyper- or hypoventilation, respiratory failure, or claustrophobia when wearing the sampling mask * Persons under guardianship or deprived of liberty * Patients with the following diseases: Cancer, Asthma, Chronic Respiratory Disease * Pregnant women * Treated with antiviral drugs upon admission or during hospitalization * Novices and soldiers in initial training

Locations (1)

IDF COVID 19 Isolation Facility

Ashkelon, Israel

Outcomes

Primary Outcomes

Correlation between Volatile Organic Compounds pattern and COVID-19 detection status.

Correlation between the set of Volatile Organic Compounds found in breath biopsy and COVID-19 detection presence in a swab test.

Time frame: Through the study completion, up to 3 months.

Secondary Outcomes

Correlation between Volatile Organic Compounds pattern and time from COVID-19 detection.

Correlation between the set of Volatile Organic Compounds found in breath biopsy and time since COVID-19 detected in a swab test.

Time frame: Through the study completion, up to 3 months.

Correlation between the set of Volatile Organic Compounds found in breath biopsy and disease intensity.

Correlation between the set of Volatile Organic Compounds found in breath biopsy and intensity of COVID-19 detected in a swab test.

Time frame: Through the study completion, up to 3 months.

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.