This study analyses clinical data prospectively collected for over a decade in several clinical databases. Electronic medical records are available since 1998. Since 2011 the subgroup of patients that undergo fertility preservation are invited to participate in a prospective study aiming at long-term follow-up after fertility preservation for oncologic and non-oncologic conditions.
In this study, the investigators aim at analyze the treatment outcomes of patients with infertility, their clinical characteristics and biochemical parameters aiming at identifying predictors for the treatment outcomes. For the cohort of patients that have undergone fertility preservation at Karolinska University Hospital, the investigators aim at investigating efficacy and safety of the procedures. The data can be expanded by using additional databases such as the Regional Cancer Registry and other registries. Analysis of data collected will allow the investigation of efficacy and safety of fertility preservation, identification of predictors for fertility outcomes,prediction of future activities and costs of the procedures.
Study Type
OBSERVATIONAL
Enrollment
50,000
fertility preservation using assisted reproductive techniques or not
Reproductive Medicine, Karolinska University Hospital
Stockholm, Sweden
RECRUITINGEfficacy and safety of fertility preservation - Long-term follow-up
Correlation between method of fertility preservation and pregnacy rate
Time frame: 2028
Clinical outcome of fertility treatments i breast cancer patients
Fertility treatment vs no fertility treatment i breastcancer patients: effect on survival
Time frame: 5-20 years post diagnosis
Clinical outcome of fertility treatments i breast cancer patients
Fertility treatment vs no fertility treatment i breastcancer patients: effect on disease free survival
Time frame: 5-7 years post diagnosis
Predictors of effictive fertility treatment
Correlation between clinical variables (age, BMI, oocyte level, administered gonadotropins, infertility) method of fertility preservation and Pregnancy rate
Time frame: patient data collected from time of treatment, pregnancy rate until end of study
Efficacy and safety of COS using GnRHa for fertility preservation in BC patients
hCG vs GnRH trigger on effect on number of cryopreserved embryos and oocytes
Time frame: Observed outcomes in patients registered between 1995 and 2017. Follow up until end of 2018.
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