This project is a single-center, prospective, self-controlled clinical study. It intends to select patients with simple medium and low degree myopia as subjects, and apply 650nm low-energy red light irradiation to the retina to observe its effect on macular microcirculation.
A total of 120 subjects are planned to be recruited and divided into 4 groups according to age and intervention, including 30 in the juvenile intervention group, 30 in the juvenile control group, 30 in the adult intervention group and 30 in the adult control group. Two intervention groups received 650nm low-energy red light irradiation treatment with a 650nm low-energy light emitter, twice a day for 3 minutes each time, The subjects were treated and followed up for 3 months. The control group was not treated and followed up for 3 months too. All subjects were followed up before treatment, at the end of the 1st month and at the end of 3rd month. Angio-oct was used as the main examination to observe and record the vascular density and blood perfusion in macular area. Axial length, diopter and OCT were used as secondary observation indexes. At the end of the experiment, the data of the intervention group and the control group were compared
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
126
650nm low energy red light eye irradiation
Chongqing Aier Eye Hosipital
Chongqing, Chongqing Municipality, China
retinal vascular density
The vascular density of the inner retinal layer in the macular area within 3×3mm was measured by angio-OCT
Time frame: 12 weeks
retinal vascular perfusion
The perfusion of the inner retinal layer in the macular area within 3×3mm was measured by angio-OCT
Time frame: 12 weeks
Choroid thickness
Distance from Bruch membrane to The inner surface of the sclera
Time frame: 12 weeks
Axial length
Distance from corneal apex to macular fovea
Time frame: 12 weeks
diopter
Myopic degree
Time frame: 12 weeks
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