Physiological Mechanisms of Therapeutic Horseback Riding Intervention Effects in a Psychiatric Population of ASD Youth

University of Colorado, Denver250 enrolled

Overview

This randomized control trial (RCT) seeks to assess the mechanisms underlying Therapeutic Horseback Riding's (THR) previously observed significant positive effects on ASD youth, particularly those with co-occurring psychiatric disorders, and to refine information on the durability, dose and sub-population effects of the intervention.

This randomized control trial (RCT) will test the hypothesis that physiological response patterns of salivary cortisol, cardiovascular, and electrodermal activity account for our previously observed significant outcomes (i.e., reduced irritability and hyperactivity, and improved social and communication), and additional outcomes (emotion regulation caregiver quality of life and crisis mental health care usage), in youth ages 6-16 yrs. with ASD and co-occurring psychiatric diagnoses randomized to a 10-week manualized THR intervention compared to a no-horse Barn Activity (BA) control (Aim 1). We will evaluate the durability of Aim 1 outcomes in the THR group compared to the BA control group six-months after the intervention period (Aim 2). Finally, we will explore dose and sub-population effects of THR and BA interventions by comparing effect size differences in THR and BA groups to (a) a 10-week wait-list control group; (b) a Hybrid intervention group (five weeks BA followed by five weeks THR); and (c) a subsample of the THR study population randomized following psychiatric hospitalization (Aim 3).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

250

Conditions

Autism Spectrum Disorder Mental Disorders

Interventions

Therapeutic Horseback RidingOTHER

Horse therapy

Barn ActivityOTHER

Horsemanship group

HybridOTHER

Ground and riding activities

Eligibility

Sex: ALLMin age: 6 YearsMax age: 17 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * documented ASD diagnosis and a co-occurring psychiatric disorder * ABC Irritability subscale score ≥8 * Leiter-III Nonverbal IQ ≥ 40 * meet Symptom Criterion score (minimum number of symptoms necessary for a DSM-V (mood, anxiety, or ADHD diagnosis) on CASI-5) * meet ASD cut-offs on the SCQ (≥ 11) and on ADOS-2 * Only one child with ASD per family to maintain independent observations * a consistent caregiver (i.e., parent or legal guardian) to complete study outcome measures Exclusion Criteria: * medical or behavioral issues that prevent participation * ward of the state * judged during riding center screen to have significant riding experience * smoking or regular use of oral, inhaled, or topical steroids on a regular basis, factors known to affect cortisol levels * Participants weighing 200 pounds or greater will be excluded due to the riding center's safety policies * Participants will not be allowed to begin baseline assessments until at least six months have passed from the time they last engaged in mounted EAAT, given pilot evidence for the six-month maintenance of THR effects.

Locations (2)

University of Colorado Anschutz Medical Campus

Aurora, Colorado, United States

Maine Health

Portland, Maine, United States

Outcomes

Primary Outcomes

Change in Aberrant Behavior Checklist-Community (ABC-C)

58-item symptom presence and severity (0-3, not a problem to severe problem) checklist of problem behaviors of children and adults with developmental disabilities in community settings. The 58 items resolve into five subscales: (1) Irritability, Agitation, (2) Lethargy, Social Withdrawal, (3) Stereotypic Behavior, (4) Hyperactivity, and (5) Inappropriate Speech.Irritability and Hyperactivity behaviors