Epidural Analgesia and Delivery of Second Twin

Abdelrady S Ibrahim, MD124 enrolled

Overview

Over an 8-year period, 124 twin pregnancies at gestational age ≥32 weeks with both twins presenting as a vertex and eligible for vaginal delivery were reviewed. Excluded were patients with the following intrapartum factors which may affect mode of delivery of second twin: 1. Presentation of the 2nd twin: breech or other than vertex; 2. Monochorionic twins; 3. Induction of labour; 4. difference in foetal weight between twin B and twin A ≥25%. The chi-square statistic was used to compare differences in the incidence of retained second twin between the groups.

The investigators conducted this prospective study in women with twins pregnancy planned for trial of vaginal delivery and gave birth between January 2014 and December 2019, in the Department of obstetrics and Gynaecology of the Sabah Maternity Hospital, Sabah Specialized Area, Kuwait. The Sabah Maternity Hospital is a tertiary care hospital for the country of Kuwait with approximately 12500 deliveries per year. The study protocol was approved by the Ethics Committee.

Study Type

OBSERVATIONAL

Enrollment

124

Conditions

Epidural Analgesia Labor Pain

Interventions

Bupivacaine-fentanylDRUG

Initial epidural bolus of 10 ml Bupivacaine 0.125% plus 50 mcg Fentanyl, followed by continuous infusion pf Bupivacaine 0.0625%™ plus 1mcg/dl Fentanyl

Eligibility

Sex: FEMALEMin age: 16 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: .gestational age of 32 weeks, determined by an early ultrasound performed in the second trimester or certain last menstrual period; (2) both twins viable; (3) eligibility for vaginal delivery as defined by twin A being cephalic; and (4) no previous cesarean section. Exclusion Criteria: * underwent an elective or repeat cesarean section * presentation of twin B at delivery other than cephalic (breech, oblique or transverse presentation * induction of labour * the difference in foetal weight between twin B and twin A at delivery ≥25% .Neonates were excluded if one was stillborn or had major congenital malformations.

Locations (1)

Assiut university faculty of medicine

Asyut, Egypt

Outcomes

Primary Outcomes

Delivery of First twin

Vaginal or C-Section

Time frame: 24 hours

Delivery of Second twin

C-Section or C-Section

Time frame: 24 hours

Data from ClinicalTrials.gov

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