Video-Assisted Thoracoscopic Surgery(VATS) is among the most common and disabling persistent pain and inflammation conditions, with increasing prevalence in the developed world, and affects women to a greater degree than men. And sleep disruption also remains a challenging problem in surgical settings. Postoperative sleep disturbances (POSD) are defined as changes in the sleep structure and quality of patients during the early stages after surgery, which are manifested as significantly shortened rapid eye movement (REM) sleep, prolonged awake time, and sleep fragmentation. Long-term POSD may increase the risk of postoperative delirium or cognitive dysfunction and delay recovery, thereby worsening the patient's physical condition. The aim of the study was to investigate the effect of sex differences on postoperative pain, inflammation and sleep quality among patients who have undergone video-assisted thoracoscopic surgery under general anesthesia.
Study Type
OBSERVATIONAL
Enrollment
213
patients receive Video-Assisted Thoracoscopic Surgery under general anesthesia
Shengjing Hospital
Shenyang, Liaoning, China
sleep quality of one night before surgery
Use Athens insomnia scale to test the sleep quality the first night before surgery
Time frame: first night before surgery
sleep quality of first night after surgery
Use Athens insomnia scale to test the sleep quality the first night after surgery
Time frame: first night after surgery
sleep quality of third night after surgery
Use Athens insomnia scale to test the sleep quality the third night after surgery
Time frame: third night after surgery
visual analog scale(VAS) score after surgery
evaluate VAS score after surgery
Time frame: one day before surgery
visual analog scale(VAS) score after surgery
evaluate VAS score after surgery
Time frame: 3 hours after surgery
visual analog scale(VAS) score after surgery
evaluate VAS score after surgery
Time frame: 8 pm the first day after surgery
postoperative adverse effect
evaluate postoperative adverse effect 24 hours after surgery
Time frame: 24 hours after surgery
perioperative inflammation function
evaluate neutrophils
Time frame: two days before surgery
perioperative inflammation function
evaluate platelet
Time frame: two days before surgery
perioperative inflammation function
evaluate lymphocyte
Time frame: two days before surgery
perioperative inflammation function
evaluate neutrophils,platelet,lymphocyte
Time frame: first days after surgery
perioperative inflammation function
evaluate neutrophils
Time frame: first days after surgery
perioperative inflammation function
evaluate platelet
Time frame: first days after surgery
perioperative inflammation function
evaluate lymphocyte
Time frame: first days after surgery
Postoperative cognition evaluation
Use MMSE Mini-Mental State Examination (MMSE) was also evaluated at Sleep preop 1, Sleep POD 1 and Sleep POD 3.18 Each correct answer is 1 point, and error or unknown is 0 point. The unsuitable one is 9 points, and refusing to answer or incomprehension is 8 points. In the total score, 8 points and 9 points are calculated by 0 points. The highest score is 30 points. The division of dementia or not is related to the degree of education. The dementia is affirmed by the patient who is illiterate and less than 17 points, the primary school is less than 20 points, and more than middle school is less than 24 points. The scores which from 27 to 30 is normal, 21 to 26 of mild, 10 to 20 of moderate, and from 0 to 9 is severe.
Time frame: one day before surgery
Postoperative cognition evaluation
Use MMSE Mini-Mental State Examination (MMSE) was also evaluated at Sleep preop 1, Sleep POD 1 and Sleep POD 3.18 Each correct answer is 1 point, and error or unknown is 0 point. The unsuitable one is 9 points, and refusing to answer or incomprehension is 8 points. In the total score, 8 points and 9 points are calculated by 0 points. The highest score is 30 points. The division of dementia or not is related to the degree of education. The dementia is affirmed by the patient who is illiterate and less than 17 points, the primary school is less than 20 points, and more than middle school is less than 24 points. The scores which from 27 to 30 is normal, 21 to 26 of mild, 10 to 20 of moderate, and from 0 to 9 is severe.
Time frame: first day after surgery
Postoperative cognition evaluation
Use MMSE Mini-Mental State Examination (MMSE) was also evaluated at Sleep preop 1, Sleep POD 1 and Sleep POD 3.18 Each correct answer is 1 point, and error or unknown is 0 point. The unsuitable one is 9 points, and refusing to answer or incomprehension is 8 points. In the total score, 8 points and 9 points are calculated by 0 points. The highest score is 30 points. The division of dementia or not is related to the degree of education. The dementia is affirmed by the patient who is illiterate and less than 17 points, the primary school is less than 20 points, and more than middle school is less than 24 points. The scores which from 27 to 30 is normal, 21 to 26 of mild, 10 to 20 of moderate, and from 0 to 9 is severe.
Time frame: third day after surgery
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