Prevention of Acute Pancreatitis After Endoscopic Interventions

Vitebsk State Medical University90 enrolled

Overview

The aim of the study is to develop a method for the prevention of acute pancreatitis after minimally invasive interventions of the bile ducts using a drug regimen.

A prospective, randomized, single-center study is planned to identify the most effective drug regimen in order to prevent the development of acute pancreatitis after transpapillary interventions of the bile ducts.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Cholangiolitis Acute Pancreatitis

Interventions

MeksibelDRUG

2 ml solution

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients with cholangiolithiasis. 2. Patients with benign formations of the bile ducts. 3. Patients with malignant formations of the bile ducts. 4. Patients with extrahepatic bile duct cysts. 5. Patients with biliary hypertension of unknown etiology. 6. Patients with cholangitis. 7. Patients with extrahepatic bile duct strictures. 8. Patients suffering from oncopathology of the head of the pancreas, complicated by obstructive jaundice. 9. Patients with malignant pathology of the pancreas. 10. Patients with benign pancreatic pathology. Exclusion Criteria: 1. ASA scale\> III (severe concomitant cardiovascular pathology) 2. Severe pathology of the respiratory system. 3. Acute period of myocardial infarction. 4. Acute period of cerebral infarction.

Locations (1)

VSMU

Vitebsk, Belarus

Outcomes

Primary Outcomes

Change in the level of inflammation and pain, assessment of severity according to the Ranson scale and Krasnogorov at 1 week

Summ points 0 - pancreatitis, 1 - mild pancreatitis, 2 - severe pancreatitis

Time frame: 1 week

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.