Tai Chi for Comorbid Depression in T2DM Patients

Inclusion Criteria: * Participants diagnosed with depression by experienced psychiatrist; * Participants diagnosed with T2DM by experienced endocrinologist; * Participants aged between 18\~75 years; * Participants with HbA1c ranges from 6.5% to 8.5%; * Participants with Hamilton Depression Scale (HAMD) (24-item-version) ranges from 20\~35 scores; * Participants passed the Physical Activity Readiness Questionnaire (PAR-Q); * Participants willing to complete 12-week intervention and 12-week follow-up. * Participants willing to sign informed consent form. Exclusion Criteria: * Participants with uncontrolled hypertension (SBP \>160mmHg or DBP \>100mmHg after taking hypotensive drugs); * Participants with severe diabetic complications; * Regular exercisers (at least 20 minutes/time, 3 times/week) in the last 3 months; * Participants with cognitive impairment (Montreal Cognitive Assessment \[MoCA\] scores \<26); * Participants with history of bipolar disorder or schizophrenia or other mental illness; * Participants with contraindications to exercise; * Participants with acute, infectious diseases, cancer, or serious neurological disease, cardiovascular disease, pulmonary disease or other serious medical conditions limiting the ability; * Participants taking psychoactive drugs; * Participants participating in other clinical trials at the same time.