Determination of Risk Factors for the Development of Obesity and Hypertension in Children According to Perinatal Programming of Metabolism

Samarkand State Medical Institute55 enrolled

Overview

to determine the risk factors for developing obesity in children with exogenous-constitutional obesity and arterial hypertension, according to the theories of early programming of metabolism

A retrospective cohort study of 55 children aged 12 to 18 years (average 14.60±0.24 years) with exogenous-constitutional obesity was conducted, with 24 girls (43.6%) and 31 (56.4%) boys. Children were identified during dispensary examinations in family clinics in Samarkand in the period 2018-2019. All the examined children belonged to the Uzbek population.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Metabolic Syndrome

Interventions

Risk FactorsOTHER

BMI in children and adolescents was compared with percentile charts developed by who for children from 5 to 19 years of age (WHO Growth Reference, 2007). Body mass index was defined as the ratio of body weight (in kg) to body length in the supine position or height in the standing position (m2).

Eligibility

Sex: ALLMin age: 12 YearsMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * SDS (standart deviation score) of body mass index (BMI) ranging from +2.0 to +3.0 Exclusion Criteria: * secondary obesity and overweight genetic syndromes, * refusal of the child and/or parents to be examined

Locations (1)

Samarkand State Medical Institute

Samarkand, Uzbekistan

RECRUITING

Outcomes

Primary Outcomes

Risk factors of metabolic syndrome

A retrospective, cohort study of 55 children aged 12 to 18 years with exogenous constitutional obesity will be conducted Children with exogenous-constitutional obesity were divided by the presence of abdominal (visceral) obesity and the presence of hypertension. Parents will be interviewed and medical records (forms 003/y and 112) of children with exogenous constitutional obesity will be analyzed. Also, on the basis of a specially developed questionnaire, children with exogenous constitutional obesity were surveyed. When conducting a survey of children and their parents, the following factors will be of particular importance: heredity, pregnancy, weight and body length at birth, the nature of nutrition in the first two years of life, eating habits, and physical activity.

Time frame: up to 36 months

Data from ClinicalTrials.gov

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