This registry will provide information about the efficacy and safety of cangrelor in a very high-risk group of patients with acute myocardial infarction undergoing PCI. It will not only include patients with cardiogenic shock, but a variety of patients not able to swallow tablets, such as those after CPR and/or with invasive or non-invasive ventilation. Therefore it will provide information about the use of cangrelor beyond the current knowledge.
This registry is a non-interventional, multicentre, retrospective cohort study in patients with acute myocardial infarction undergoing PCI after CRP, ventilated and/or with cardiogenic shock. The study is purely observational; data will be documented retrospectively based on available medical records. No additional data will be collected, no study-related treatment will be initiated. About 10 - 20 high-volume PCI clinics in Germany treating patients with myocardial infarction are eligible for participation. Participating sites will be given a maximum of 6 months for retrospectively documenting eligible patients. Eligible are all patients with acute myocardial infarction (STEMI, NSTEMI) who underwent PCI after CRP, ventilated and/or with cardiogenic shock and were treated with cangrelor during index procedure. It is planned to enrol about 400 patients in total. Patient characteristics, procedural details and clinical events occurring during the period between index MI and discharge or death (whichever came first) will be documented based on the relevant existing medical charts of the patients.
Study Type
OBSERVATIONAL
Enrollment
303
Universitätsklinikum Graz
Graz, Austria
Klinik Ottakring
Vienna, Austria
Fürst-Stirum Klinikum Bruchsal
Bruchsal, Germany
Universitätsklinikum Freiburg
Freiburg im Breisgau, Germany
Definite stent thrombosis
Rate of stent thromboses
Time frame: from procedure for index MI up to 48 hours
Recurrent myocardial infarction
Rate of recurrent myocardial infarction according to the universal definition of MI
Time frame: from procedure for index MI up to 48 hours
Definite stent thrombosis
Rate of stent thromboses
Time frame: from procedure for index MI until discharge from hospital or intrahosptal death, whichever came first; up to 30 days
Recurrent myocardial infarction
Rate of recurrent myocardial infarction according to the universal definition of MI
Time frame: from procedure for index MI until discharge from hospital or intrahosptal death, whichever came first; up to 30 days
Bleeding complications
Rate of bleeding complication according to BARC definition
Time frame: from procedure for index MI until discharge from hospital or intrahosptal death, whichever came first; up to 30 days
Mortality
Rate of death
Time frame: from procedure for index MI until discharge from hospital; up to 30 days
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Klinikum Leverkusen
Leverkusen, Germany
Klinikum Ludwigshafen
Ludwigshafen, Germany
Universitätsklinikum Mannheim
Mannheim, Germany
Hegau-Bodensee Klinikum Singen
Singen, Germany
Krankenhaus Maria-Hilf
Stadtlohn, Germany
Universitätsklinikum Tübingen
Tübingen, Germany