Fast Reversal of Warfarin and Early Surgery in Patients With Trochanteric Hip Fracture A Case-control Study

Karolinska Institutet198 enrolled

Overview

A retrospective case-control study. To evaluate if early surgery within 24hours of troch or subtrochanteric hip fractures using intramedullary nailing is safe in patients on warfarin treatment after fast reversal of the warfarin effect

Study Type

OBSERVATIONAL

Enrollment

198

Conditions

Trochanteric Hip Fractures Warfarin Medication Early Surgery

Eligibility

Sex: ALLMin age: 60 Years

Medical Language ↔ Plain English

Exclusion Criteria: * Pathological fracture * Late presentation to the hospital * Other injuries

Locations (1)

Södersjukhuset

Stockholm, Sjukhusbacken 10, Sweden

Outcomes

Primary Outcomes

Transfusion rates

Hb value (g/dl)

Time frame: Pre-surgery

Transfusion rates

Transfusion rate (n)

Time frame: Pre-surgery

Transfusion rates

Hb value (g/dl)

Time frame: During the surgery

Transfusion rates

Transfusion rate (n)

Time frame: During the surgery

Transfusion rates

Hb value (g/dl)

Time frame: 2-4 days after the surgery

Transfusion rates

Transfusion rate (n)

Time frame: 2-4 days after the surgery

adverse events

Number of patients with a myocardial infarction, stroke, pulmonary embolism, deep venous thrombosis, sepsis, pneumonia, urinary tract infection, pressure ulcer, or any adverse events.

Time frame: Immediately after the surgery

mortality

The number of deaths

Time frame: Immediately after the surgery

mortality

The number of deaths

Time frame: 30-days after the surgery

mortality

The number of deaths

Time frame: 1 year after the surgery

Data from ClinicalTrials.gov

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