This study is evaluating whether adding stereotactic radiotherapy (a new, more focused type of radiotherapy) to treat all the tumours that are present will improve outcomes or not compared to drugs alone for patients who are negative on conventional imaging and positive on PSMA PET scan
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
SBRT to all sites of metastatic disease as seen on PSMA PET scan
Intermittent Hormone Therapy per physician discretion (Min. 8 months)
Odette Cancer Centre
Toronto, Ontario, Canada
Proportion of eligible patients who enroll onto the study
The primary purpose of this feasibility study is to measure the proportion of patients who are willing to enter this randomized trial
Time frame: Through accrual completion, approx 2 years
Side Effects and Effectiveness
An important secondary purpose is to measure the side effects and effectiveness of adding stereotactic radiotherapy to all sites of disease to intermittent hormone therapy compared to intermittent hormone therapy alone, using CTCAE v.5
Time frame: Through study completion, approx 5 years
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