The main objectives of this study are 1. to establish the prevalence of SARS-CoV-2 in schools and kindergartens in the State of Mecklenburg-Vorpommern in autumn and winter 2020/2021 2. to monitor the future spread of the disease by assessing serological responses to SARS-CoV-2 in teachers and childcare educators over time
Detailed Description: This study aims to collect information on teachers and childcare educators as well as on pupils and preschoolers in the State of Mecklenburg-Vorpommern Over a 5 month period, 5 study visits per participant are planned. At each visit, nasal/throat swabs (for PCR testing) will be collected and participants will be asked to fill in a questionnaire (asking for SARS-CoV-2 risk factors, perceived risk, and impact of the pandemic on their quality of life). In adults, additional blood samples (for SARS-CoV-2 antibody testing) will be collected at the first and the last study visit. This will help to gain a better understanding of viral load and antibody development over time. The remaining blood samples will be stored in a repository for future research. The study is part of a modular SARS-CoV-2-research programme of the University Medicine Greifswald.
Study Type
OBSERVATIONAL
Enrollment
142
SARS-CoV-2 PCR
Anti-SARS-CoV-2 antibody testing (IgA and IgG ELISA)
Greifswald University Medicine
Greifswald, Germany
Share of participants with SARS-CoV-2 detectable in PCR
Percentage of SARS-CoV-2 PCR positive participants (children and educational staff)
Time frame: 5 months
Seroprevalence of SARS-CoV-2 antibodies
Percentage of Anti-SARS-COV2 S protein IgA and IgA ELISA positive participants (educational staff)
Time frame: At study inclusion
Seroprevalence of SARS-CoV-2 antibodies
Percentage of Anti-SARS-COV2 S protein IgA and IgA ELISA positive participants (educational staff)
Time frame: 5 months
SARS-CoV-2 risk factors, perceived risk of infection, and impact of the pandemic on quality of life
As assessed by a monthly questionnaire
Time frame: At study inclusion
SARS-CoV-2 risk factors, perceived risk of infection, and impact of the pandemic on quality of life
As assessed by a monthly questionnaire
Time frame: 1 month
SARS-CoV-2 risk factors, perceived risk of infection, and impact of the pandemic on quality of life
As assessed by a monthly questionnaire
Time frame: 2 months
SARS-CoV-2 risk factors, perceived risk of infection, and impact of the pandemic on quality of life
As assessed by a monthly questionnaire
Time frame: 3 months
SARS-CoV-2 risk factors, perceived risk of infection, and impact of the pandemic on quality of life
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As assessed by a monthly questionnaire
Time frame: 4 months
SARS-CoV-2 risk factors, perceived risk of infection, and impact of the pandemic on quality of life
As assessed by a monthly questionnaire
Time frame: 5 months
Share of participants with SARS-CoV-2 detectable in PCR
Percentage of SARS-CoV-2 PCR positive participants (children and educational staff)
Time frame: At study inclusion
Share of participants with SARS-CoV-2 detectable in PCR
Percentage of SARS-CoV-2 PCR positive participants (children and educational staff)
Time frame: 1 month
Share of participants with SARS-CoV-2 detectable in PCR
Percentage of SARS-CoV-2 PCR positive participants (children and educational staff)
Time frame: 2 months
Share of participants with SARS-CoV-2 detectable in PCR
Percentage of SARS-CoV-2 PCR positive participants (children and educational staff)
Time frame: 3 months
Share of participants with SARS-CoV-2 detectable in PCR
Percentage of SARS-CoV-2 PCR positive participants (children and educational staff)
Time frame: 4 months