We hypothesized that local administration of tranexamic acid will minimize blood loss and blood product administration in pediatric patient undergoing scoliosis surgery
Spine surgery in paediatrics is frequently associated with substantial blood loss. Blood product adminestration in children has many complications that are not fully known. There are many modalities currently available to reduce blood loss in pediatric patients. Tranexamic acid is tissue plasminogen activator inhibitor that reduce perioperative blood loss. To date, no studies have investigated effect of local administration of tranexamic acid in pediatric population undergoing scoliosis surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
30
Local subfascial and intramuscular infiltration will be performed by surgeon at levels of fixation prior to skine incision
Local subfascial and intramuscular infiltration will be performed by surgeon at levels of fixation prior to skine incision
Intraperative blood loss in both groups
amount of blood/kg(ml/kg)
Time frame: period of surgery(1-2 hours)
post-operative blood loss
amount of blood in drain after surgery
Time frame: 24 hours
Blood product admenestration
units of blood given during surgery
Time frame: duration of procedure(1-2 hours)
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