This study was designed to demonstrate incidence of biliary complication rates after living donor liver transplantation according to the implantation of external biliary drainage throug duct-to-duct anastomosis site.
Biliary complication is the most common complications after liver transplantation, and it happens more often after living donor liver transplantation (LDLT) than deceased donor liver transplantation. Many transplant centers adopted their own methods to improve biliary complications after LDLT. One suggested method is the application of external biliary drainage (EBD). A prospective study was planned to demonstrate effect of EBD on biliary complication after LDLT. Patients who underwent LDLT with duct-to-duct anastomosis will be randomly assinged to application of EBD or conventional duct-to-duct anastomosis without EBD according to a computer generated randomization sequence and allocated in a 1:1 ratio to one of two groups. Primary outcome is biliary complication incidence 1 year after LDLT.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
124
Application of external biliary drainage through duct-to-duct anastomosis
Seoul National University Hospital
Seoul, South Korea
RECRUITINGIncidence of biliary complication within 1 year after LDLT
Biliary stricture/leakage
Time frame: 1 year
Incidence of biliary complication within 3 year after LDLT
Biliary stricture/leakage
Time frame: 3 year
Complication associated with external biliary drainage
Dislocation, retraction, reposition, leakage through tube site, hemorrhage
Time frame: 3 year
Graft survival
Survival of liver graft
Time frame: 3 year
Patient survival
Patient survival after LDLT
Time frame: 3 year
Patient-reported outcome
Questionnaire survey
Time frame: 3 year
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.