Non-contact DCS-Speckle Multi-parameter Imaging for Neurological Diseases

Ting Li60 enrolled

Overview

This study aims to evaluate brain injuries and brain edema with non-contact DCS-Speckle multi-parameter imager.

Brain injuries includes acute and chronic injuries located in cerebral hemispheres, cerebellum, and brain stem, while brain edema is increased intracellular or extracellular fluid in brain tissue. Early diagnosis is helpful to improve the cure rate and reduce sequelae. This study aims to evaluate brain injuries and brain edema with non-contact DCS-Speckle multi-parameter imager, so as to provide reference diagnostic criteria by image artificial intelligence analysis.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Brain Injuries Brain Edema Optical Imaging

Interventions

Non-contact DCS-Speckle multi-parameter imagingDIAGNOSTIC_TEST

The protocol consists of 2-min resting, 6-min stationary state and 2-min resting, with monitoring data continuously by the DCS-Speckle.

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who have had brain damage. * Patients who have had brain edema. * Healthy people who are interested in non-contact DCS-Speckle multi-parameter imaging Exclusion Criteria: * Patients who are in pregnancy or have plan to conception. * Patients who have vertebra surgery or have plan to surgery. * Patients who are inappropriate to join this trial judged by the radiologists or specialists. * AIDS, Active Hepatitis, Tuberculosis, Syphilis * Patients who regularly take anticoagulants, antiplatelet drugs

Locations (1)

NIRS assessment for brain death

Tianjin, Tianjin Municipality, China

Outcomes

Primary Outcomes

Imaging data

Imaging data collected during the non-contact DCS-Speckle imaging instrument

Time frame: 1 day during the whole experiment

Secondary Outcomes

Diagnostic report fMRI data

Patients' medical record and diagnostic report

Time frame: 1 day during the whole experiment

Data from ClinicalTrials.gov

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