Perioperative Management in Gynaecological Carcinoma Surgery

Inclusion Criteria: * informed consent as documented by signature * women with gynaecological carcinoma surgery with hemoglobin level between 90-120 g/I and serum ferritin \< 100 µg/I (or ferritin index \< 3.19) at recruitment * pregnancy test negative in women younger than 50 years Exclusion Criteria: * known hypersensitivity or allergy to ferric carboxymaltose or tranexamic acid * history or present laboratory signs of bleeding disorders, coagulopathy or thromboembolic events * history of myocardial infarction within the last year, present unstable angina or severe coronary disease * increased plasma creatinine levels above 250 µmol/I * inability to follow the procedures of the study (language problems, severe psychiatric or mental disorders) * iron overload * current administration of intravenous iron or previous intravenous iron therapy or blood transfusion within three months * date of scheduled surgery is outside 28 days after the date of recruitment * other clinically significant concomitant disease states (e.g., hepatic dysfunction, cardiovascular disease, etc.) * participation in another study with investigational drug within the 30 days * enrolment of the investigator, his/her family members, employees and other dependent persons.