We aimed to measure the changes in your blood values caused by different but safe oxygen values used by us during your heart surgery under laboratory conditions.
Hyperoxia is often preferred due to the risk of tissue hypoxia that may develop in cardiac surgery. It is thought that with hyperoxemia, ischemia reperfusion damage increases, microcirculation is impaired and tissue oxygenation is impaired.Oxidative damage occurs in cases of increased oxidative stress and impaired antioxidant balance.It was aimed to investigate oxidative damage by recording modified albumin and thiol disulfide in blood simultaneously by recording arterial oxygen levels at determined times during cardiac surgery.
Study Type
OBSERVATIONAL
Enrollment
100
Venous blood samples taken during the operation and at the 48th hour after the operation will be examined after appropriate procedures.
University of Health Sciences Bursa Yüksek İhtisas Training and Research Hospital
Bursa, Turkey (Türkiye)
assessment of oxidative damage
To measure the degree of oxidative damage in the patient's blood at different oxygen values used in cardiac bypass surgeries with thiol disulfide homeostasis and ischemia-modified albumin at times determined.
Time frame: 48 hours after operation
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