Comparison of the Efficacy of Irrigation With Epinephrine or Tranexamic Acid on Visual Clarity

Haseki Training and Research Hospital100 enrolled

Overview

The primary aim of this report is to determine whether there is a difference between Epinephrine and Tranexamic acid in providing visual clarity during arthroscopic rotator cuff tear repair.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Enrollment

100

Conditions

Rotator Cuff Tears

Interventions

tranexamic acidDRUG

Tranexamic acid is added to the irrigation fluid used in arthroscopic shoulder surgery.

EpinephrineDRUG

Epinephrine is added to the irrigation fluid used in arthroscopic shoulder surgery.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * • Age \> 18 years * American Society of Anesthesiologist Physical Status Classification System : 1-2 * Undergoing a full arthroscopic double-row repair due to full-thickness cuff tear * Being willing to participate the study Exclusion Criteria: * • Age \< 18 years * American Society of Anesthesiologist Physical Status Classification System ≥3 * Concomitant cardiac diseases * Concomitant bleeding disorder or coagulopathy * Diabetes mellitus * Being pregnant * Use of contraceptive pills * A history of previous shoulder surgery * Uncontrolled hypertension during the operation (\>180/110 mm Hg) * Unrepairable rotator cuff tears * Being unwilling to participate the study

Locations (1)

Haseki Training and Research Hospital

Istanbul, Turkey (Türkiye)

Outcomes

Primary Outcomes

Visual analog scale

Visual analog scale will be rated by surgeon. While 0 is the worst score with no clear vision, 10 was noted as the best score for visual clarity.

Time frame: through study completion, an average of 2 year

Secondary Outcomes

total operating time

period in minutes from the time the arthroscope was inserted into the glenohumeral joint until the termination of the arthroscopic procedure

Time frame: through study completion, an average of 2 year

average mean arterial pressure

mean arterial pressure per operation.

Time frame: through study completion, an average of 2 year

Data from ClinicalTrials.gov

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