This study will compare the impact of two systems above low-flow nasal cannula on the arterial oxygen tension in patients with COVID-19. The two systems are the Surgical Mask (SM) and the Double-Trunk Mask (DTM).
Hospitalized patients with COVID-19 typically present with hypoxemia. In some patients, hypoxemia can be corrected with low flow nasal cannula. When placed above nasal cannula, some systems have demonstrated their interest in improving the performance of patient's oxygen delivery. For example, two recent studies have shown that adding a Double-Trunk Mask (DTM) or Surgical Mask (SM) above nasal cannula has the potential to improve the PaO2 despite no change in oxygen output (Duprez et al., J Clin Monit Comput 2020; Montiel et al., Ann Intensive Care 2020). However, there is no study comparing the relative effectiveness of these 2 systems.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
27
The standard oxygen delivery system (low-flow nasal cannula or oxygen mask) is worn by the patient for 1 hour.
The Double-Trunk Mask above the standard oxygen delivery system (low-flow nasal cannula or oxygen mask) is worn by the patient for 1 hour.
The Surgical Mask above the standard oxygen delivery system (low-flow nasal cannula or oxygen mask) is worn by the patient for 1 hour.
Cliniques universitaires Saint-Luc
Brussels, Belgium
Changes in PaO2
Oxygen tension (PaO2) in mmHg will be analyzed from a sample taken from the arterial system
Time frame: At baseline and 30 minutes after wearing the randomized oxygen delivery system
Change in PaCO2
Carbon dioxide tension (PaCO2) in mmHg will be analyzed from a sample taken from the arterial system.
Time frame: At baseline and 30 minutes after wearing the randomized oxygen delivery system
Change in pH
Potential of Hydrogen (pH) will be analyzed from a sample taken from the arterial system.
Time frame: At baseline and 30 minutes after wearing the randomized oxygen delivery system
Change in respiratory rate
Respiratory rate is measured during one minute by visual inspection.
Time frame: At baseline, 30 minutes and 60 minutes after wearing the randomized oxygen delivery system
Change in dyspnea
Dyspnea is rated with a visual analogic scale (0 to 100mm).
Time frame: At baseline and 60 minutes after wearing the randomized oxygen delivery system
Change in O2 output
The O2 output will be adjusted to recover the baseline SpO2 reading. The O2 output will be read from the position of the ball inside the flowmeter.
Time frame: At 30 minutes and 60 minutes after wearing the randomized oxygen delivery system
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