To compare the effect of IPL combined with lipiflow and IPL combined with meibomian gland massage in treating meibomian gland dysfunction of different degrees ,focusing on effective rate, lasting time and changes of meibomian gland function and morphology.
To divide all participants into two groups, group one treated with IPL combined with Lipiflow and group two treated with IPL combined with meibomian gland massage.The following parameters were recorded after treatment: the effective rate, lasting time and changes of meibomian gland function and morphology.All parameters were compared between the two groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
100
To treat patients with MGD using intense pulsed light combined with lipiflow
To treat patients with MGD using intense pulsed light combined with meibomian gland massage
ocular surface disease index(OSDI)
The OSDI is assessed on a scale of 0 to 100,with higher scores representing greater disability
Time frame: 6 months
meibomian gland expressibility score and meibum quality score
The score is on a scale of 0 to 6.The higher scores, the severity of the meibomian gland function(the highest score is 6 and the lowest score is 0)
Time frame: 6 months
meibomian gland dropout score
the higher scores, the severity of the meibomian gland morphology(The highest score is 6 and the lowest score is 0)
Time frame: 6 months
Breakup time
the shorter time, the poorer of the tear film stability
Time frame: 6 months
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