This is a cross-sectional study on the use of personalized blood flow restriction during rehabilitation exercises and its effects on biomechanics on people who have had an anterior cruciate ligament reconstruction and healthy controls
Rehabilitation after surgical reconstruction of the anterior cruciate ligament (ACL) aims to reestablish the function of the knee. However, regaining previous levels of strength is challenging, with long-term muscle weakness frequently reported and thought to play a key role in the increased risk of knee osteoarthritis for individuals with a history of ACL damage. Effectively building muscle strength requires exercises with high resistance loads, however the joint stress and risk of further injury makes these types of activities inappropriate and unsafe for those rehabilitating after ACL reconstruction surgery and other injuries. Personalized blood flow restriction (BFR) training is a technique where the blood flow to the muscles being exercised is controlled by a pressure cuff to a predefined level, and has been shown to increase strength while exercising with significantly lower loads. Early results have been promising, however the effects of BFR on the biomechanics of the exercise as well as the acceptability in the ACL reconstruction population have not been explored. In this application, we propose a cross-sectional study designed to test the acceptability of BFR training for those undergoing rehabilitation from ACL reconstruction surgery and healthy controls during free standing exercises. We will also investigate the biomechanical effects of this rehabilitation technique. This application is part of a larger program of musculoskeletal research in this area being developed by the team. The results from the proposed project will inform the design of a clinical trial of personalized BFR after ACL reconstruction.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
40
Intervention restricts blood flow to the lower limb as a percentage of the limb occlusion pressure
University of Washington Medical Center
Seattle, Washington, United States
Knee Flexion
Maximum difference in flexion motion of knee while performing exercise between baseline and blood flow restriction condition. Measured in degrees
Time frame: 6 minutes
Knee Internal Rotation
Maximum difference in internal rotation of knee while performing exercise between baseline and blood flow restriction condition. Measured in degrees
Time frame: 6 minutes
Knee Varus
Maximum difference in varus motion of knee while performing exercise between baseline and blood flow restriction condition. Measured in degrees
Time frame: 6 minutes
Hip Flexion
Maximum difference in flexion motion of hip while performing exercise between baseline and blood flow restriction condition. Measured in degrees
Time frame: 6 minutes
Hip Adduction
Maximum difference in adduction motion of hip while performing exercise between baseline and blood flow restriction condition. Measured in degrees
Time frame: 6 minutes
Hip Internal Rotation
Maximum difference in internal rotation motion of hip while performing exercise between baseline and blood flow restriction condition. Measured in degrees
Time frame: 6 minutes
Knee Extension Moment
Maximum difference in extension moment of knee while performing exercise between baseline and blood flow restriction condition. Measured in Newton meters per kilogram
Time frame: 6 minutes
Knee Internal Rotation Moment
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Maximum difference in internal rotation moment of knee while performing exercise between baseline and blood flow restriction condition. Measured in Newton meters per kilogram
Time frame: 6 minutes
Knee Adduction Moment
Maximum difference in adduction moment of knee while performing exercise between baseline and blood flow restriction condition. Measured in Newton meters per kilogram
Time frame: 6 minutes
Hip Extension Moment
Maximum difference in extension moment of hip while performing exercise between baseline and blood flow restriction condition. Measured in Newton meters per kilogram.
Time frame: 6 minutes
Hip Adduction Moment
Maximum difference in adduction moment of hip while performing exercise between baseline and blood flow restriction condition. Measured in Newton meters per kilogram
Time frame: 6 minutes
Hip Internal Rotation Moment
Maximum difference in internal rotation moment of hip while performing exercise between baseline and blood flow restriction condition. Measured in Newton meters per kilogram
Time frame: 6 minutes
Exercise Difficulty Score
Numerical Analogue Scale, 0-10, higher scores indicate greater difficulty
Time frame: 6 minutes
Exercise Discomfort Score
Numerical Analogue Scale, 0-10, higher scores indicate greater discomfort
Time frame: 6 minutes