To develop and investigate an unobtrusive technology for long-term monitoring of autonomic nervous system (ANS) function's response to daily physical stressors and exercise training for elderly patients with different frailty stages.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
100
Subjects randomized to the IG will participate at home training program that will last 12 weeks and consists of endurance, flexibility, balance and cardiovascular resistance training performed with low to moderate intensity, in 20-60 minutes sessions, five times a week. Study participants will be asked to wear wrist and chest unobtrusive devices during active day time or at least during the training session and two hours before and after.
LUHS hospital Kaunas Clinics Rehabilitation hospital of Kulautuva
Kaunas, Kulautuva, Lithuania
Autonomic nervous function by Heart Rate Recovery (HRR)
HRR (beats per minute) is a difference of the maximal HR obtained during stress testing and HR during the recovery period: HR30-360 the decay of heart rate from 30 to 360 s after the recovery onset.
Time frame: 3 weeks
Autonomic nervous function by Heart Rate Recovery (HRR)
HRR (beats per minute) is a difference of the maximal HR obtained during stress testing and HR during the recovery period: HR30-360 the decay of heart rate from 30 to 360 s after the recovery onset.
Time frame: 12 weeks
Autonomic nervous function by Heart Rate Fragmentation (HRR)
HRF measured by RR interval indexes:percentage of inflection points (PIP), inverse of the average length of the acceleration/deceleration segments (IALS), percentage of short segments (PAS), percentage of alternation segments (PSS).
Time frame: 3 weeks
Autonomic nervous function by Heart Rate Fragmentation (HRR)
HRF measured by RR interval indexes:percentage of inflection points (PIP), inverse of the average length of the acceleration/deceleration segments (IALS), percentage of short segments (PAS), percentage of alternation segments (PSS).
Time frame: 12 weeks
Cardiopulmonary exercise capacity by maximal oxygen consumption (peakVO2)
PeakVO2 measured with spiroergometry by millilitres of oxygen per kilogram of body mass per minute
Time frame: 3 weeks
Cardiopulmonary exercise capacity by maximal oxygen consumption (peakVO2)
PeakVO2 measured with spiroergometry by millilitres of oxygen per kilogram of body mass per minute
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Time frame: 12 weeks
Cardiopulmonary exercise capacity by maximal load (maxWatt)
Maximal load measured with spiroergometry by maximal watts
Time frame: 3 weeks
Cardiopulmonary exercise capacity by maximal load (maxWatt)
Maximal load measured with spiroergometry by maximal watts
Time frame: 12 weeks
Functional capacity by six minutes walking test (6MWT)
6MWT measured by meters
Time frame: 3 weeks
Functional capacity by six minutes walking test (6MWT)
6MWT measured by meters
Time frame: 12 weeks
Physical performance by Timed up and Go test (TUG)
TUG measured by seconds
Time frame: 3 weeks
Physical performance by Timed up and Go test (TUG)
TUG measured by seconds
Time frame: 12 weeks
Gait evaluation by step time
Step time measured with treadmill ergometer by seconds
Time frame: 3 weeks
Gait evaluation by step time
Step time measured with treadmill ergometer by seconds
Time frame: 12 weeks
Frailty level by Edmonton frailty scale (EFS)
0-17 points, the higher the worse. The EFS assesses 9 domains: cognition, general health status, functional independence, social support, medication use, nutrition, mood, continence, and functional performance.
Time frame: 3 weeks
Frailty level by Edmonton frailty scale (EFS)
0-17 points, the higher the worse. The EFS assesses 9 domains: cognition, general health status, functional independence, social support, medication use, nutrition, mood, continence, and functional performance.
Time frame: 12 weeks