A Study to Compare the Efficacy of GNS561 Versus Standard of Care in Patients With SARS-CoV-2 (COVID-19) Infection

Inclusion Criteria: * Documented diagnosis of COVID-19 (diagnostic test performed in a certified laboratory). * Clinical status: Hospitalized for moderate COVID-19 with News2 score between 5 and 6 Exclusion Criteria: * Patient known to have intolerance or hypersensitivity to chloroquine or any quinoline derivates (quinine, tafenoquine, hydroxychloroquine, mefloquine). * History of QT prolongation (QTc ≥ 500 ms) or QTc ≥ 500msec at screening or bradycardia \< 50/mn * Current use of loop diuretics and potassium supplementation or documented history of hypokalemia or hypokalemia \< 3.5mmol/l at screening * Prior allogeneic bone marrow transplantation or solid organ transplant in the past. * Pregnant or breastfeeding patient, or expecting to conceive children within the projected duration of the trial, starting with the screening visit through 6 months after the last dose of study drugs.