This is a transversal monocentric study comparing two groups of women (group 1, patient group : patients who have been treated for a breast cancer with taxane-based chemotherapy ; group 2, control group : healthy volunteers). The aim of this study is to evaluate if a difference exists regarding the maximal isometric muscle strength between group 1 and 2.
All subjects will be evaluated a single time during two hours. For patients from group 1 the evaluation should take place within the two weeks that follow the end of adjuvant treatment. There is no specificity regarding evaluation of volunteers from group 2, their evaluation can take place at any time.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
30
at inclusion
Institut de Cancerologie Strasbourg Europe
Strasbourg, France
Maximal isometric muscle strength for knee extensors
Measured with force sensors. Significant differences between the two groups will be assessed
Time frame: At Inclusion
Number of Participants with neuromuscular fatigue
Assessment using surface electromyography. Significant differences between the two groups will be assessed.
Time frame: At Inclusion
Number of Participants with neuromuscular fatigue
Assessment using percutaneous electric nerve stimulation. Significant differences between the two groups will be assessed.
Time frame: At Inclusion
Number of Participants with neuromuscular fatigue
Assessment using transcranial magnetic stimulation. Significant differences between the two groups will be assessed.
Time frame: At Inclusion
Number of Participants with subjective fatigue.
Questionnaire Functional Assessment of Chronic Illness Therapy - Fatigue Scale (FACIT-F) version 4. Significant differences between the two groups will be assessed.
Time frame: At Inclusion
Number of Participants with muscle architecture.
Assessment using muscle ultrasonography. Significant differences between the two groups will be assessed.
Time frame: At Inclusion
Number of Participants with body composition.
Assessment using bio-impedance analysis. Significant differences between the two groups will be assessed.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: At Inclusion