The aim of the study is to develop, verify and optimize the ERAS protocol for cardiac surgery.
The aim of the study is to develop, verify and optimize the ERAS protocol for cardiac surgery, thereby improving the overall prognosis of cardiac surgery patients, reducing the incidence of complications, and shortening the length of hospital stay.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
400
Patient Education Preoperative Oral Carbohydrate Loading Nutritional Optimization Glycemic Control Anemia Correction Preoperative Hair Removal
Anesthetic Technique (Multimodal Analgesia) Antibiotics Glycemic Control Blood Transfusion Blood Conservation Optimization of Hemodynamics Protective Lung Ventilation Strategy Optimization of Anesthetic Depth Optimization of CPB Management
Postoperative Analgesia Temperature Management Renal Protection Glycemic Control Early Extubation Early Oral Intake Maintain Drain Patency and Early Removal Early Ambulation Thromboprophylaxis
The First Affiliated Hospital of AnHui Medical University
Hefei, Anhui, China
Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Shanghai, Shanghai Municipality, China
Shanghai Chest Hospital Affiliated to Shanghai Jiaotong University
Shanghai, Shanghai Municipality, China
Zhongshan Hospital Affiliated to Fudan University
Shanghai, Shanghai Municipality, China
Length of hospital stay
Time frame: Within 1 month after surgery
Length of ICU stay
Time frame: Within 1 month after surgery
Duration of mechanical ventilation after surgery
Time frame: Within 1 week after surgery
Postoperative bowel motility
Time frame: within 1 month after surgery
Overall hospitalization costs
Time frame: Within 3 months after surgery
Transfusion requirements
Time frame: within 1 month after surgery
Postoperative acute pain
assessed using the Visual Analog Scale (VAS), ranging from 0 (no pain) to 10 (worst imaginable pain)
Time frame: within 1 month after surgery
Quality of recovery
assessed using the 15-item Quality of Recovery-15 (QoR-15) scale, with each item scored from 0 (very poor) to 10 (very good), for a total score of 150
Time frame: within 1 month after surgery
Chronic pain
Diagnostic Criteria of Chronic (postsurgical) Pain 1. Chronic pain (persistent or recurrent for longer than 3 months) is present. 2. The pain began or increased in intensity after surgery. 3. The pain is in an area of preceding surgery. 4. The pain persisted for at least 3 months after the initiating event. 5. The pain is not better accounted for by an infection, a malignancy, a pre-existing pain condition or any other alternative
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Time frame: within 6 months after surgery
Patient's subjective comfort
assessed using the Bruggrmann Comfort Scale (BCS),it is a scoring tool for assessing patient comfort, ranging from 0 (persistent pain) to 4 (pain-free even when coughing)
Time frame: within 6 months after surgery
Postoperative complications
Including mortality and complications both in-hospital and post-discharge
Time frame: within 6 months after surgery