Bimanual Motor Skill Learning Through Robotics in Chronic Cerebellar Stroke Survivors and Healthy Individuals

N/AActive Not RecruitingNCT04642599

University Hospital of Mont-Godinne50 enrolled

Overview

To test capacity of chronic cerebellar stroke patients and healthy individuals to learn and retain a complex bimanual motor skill, trained on the neurorehabilitation robot REAplan® (bimanual version).

Over 3 consecutive days, healthy individuals and chronic cerebellar stroke patients (1) will be evaluated and (2) will train on the neurorehabilitation robot REAplan®. They will practice several tasks on the robot REAplan® (bimanual version), requiring either movements with the affected arm (unimanual tasks) or complex, coordinated movements with both arms (bimanual tasks). In addition, several "classical" clinical scales and tests will be used to evaluate overall motor-sensory-cognitive functions (clinical tests, questionnaires, ...). Hand/digits motor function will be also evaluated with the kinetic device DexTrain®.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Chronic Cerebellar Stroke Healthy Individuals (Controls)

Interventions

Bimanual motor skill learning with the REAplan® rehabilitation robotDEVICE

REAplan® rehabilitation robot: training to perform complex, coordinated, bimanual movements

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 YearsHealthy volunteers:

Medical Language ↔ Plain English

STROKE PATIENTS: Inclusion Criteria: * having a chronic cerebellar stroke (\>6 months) * aged 18-90 years * with a demonstrated stroke (ischemic or hemorrhagic) lesion on brain imaging Exclusion Criteria: * difficulty in understanding or executing commands * drug/alcohol abuse * severe aphasia / cognitive deficits interfering with study * inability to voluntarily move the affected arm (i.e. complete paralysis of the arm) * multiple strokes / dementia / psychiatric condition HEALTHY INDIVIDUALS: Inclusion Criteria: * 18-90 years Exclusion Criteria: * neurological conditions interfering with the study * drug/alcohol abuse * pyschiatric condition

Locations (1)

CHU UCL Namur, Mont-Godinne, Neurology Department, Stroke Unit

Yvoir, Namur, Belgium

Outcomes

Primary Outcomes

Change in bi-SAT

Bimanual Speed/Accuracy Trade-off measured by the REAplan robot bimanual Speed/Accuracy Trade-off: mathematical computation of the relationship bewteen speed and accuracy

Time frame: Change between day 1 to 3

Change in bi-CO

Bimanual Coordination factor measured by the REAplan robot bimanual Coordination factor : mathematical measure of the phase coherence between velocities of both arms

Time frame: Change between day 1 to 3

Secondary Outcomes

bi-SAT

On bimanual REACHING (REAplan robot) bimanual Speed/Accurady Trade-off: mathematical computation of the relationship

Time frame: Day 1 + day 3

bi-CO

On bimanual REACHING (REAplan robot) bimanual Coordination factor: mathematical measure of the phase coherence between velocities of both arms

Time frame: Day 1 + day 3

change in bi-Force

Bimanual forces : forces exerted in the wrong direction by each arm (Newtons)

Time frame: Change between day 1 to 3

bi-Force

On bimanual REACHING (REAplan robot) bimanual forces : forces exerted in the wrong direction by each arm (Newtons)

Time frame: Day 1 + day 3

bi-smoothness

On bimanual REACHING (REAplan robot) Smoothness of movement : Spectral Arc Length (SPARC)

Time frame: Day 1+ day 3

bi-error

Data from ClinicalTrials.gov

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