Coronavirus Disease-19 (COVID-19) is a global pandemics which affects many organs and systems with a range of morbidities and high mortality rates. There are a number of studies revealed that COVID-19 may affect the testes and male genital tract which may in turn disrupt the gonadal functions.The current study aimed to evaluate the effect of COVID-19 on semen parameters and sex-related hormone levels.
In this current study, the investigators aimed to elucidate the alteration in semen parameters of the infertile male patients who had been infected with SARS-CoV-2, through the comparison of the spermiogram results which were reported before and after the diagnosis of COVID-19. The investigators also aimed to evaluate the impact of COVID-19 on the sex-related hormone levels as follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone (T). The current study is conducted in Ankara City Hospital, the highest capacity tertiary health care center of the capital town of Turkey. The study included 21 patients who applied to Ankara City Hospital, Andrology Clinic for male infertility up to 05 October, 2020 and have had the semen analyses reported before and after the clinically confirmed diagnosis of COVID-19 through reverse transcriptase PCR. Besides the semen analyses, 8 of these 21 patients have also the had the reported levels of T, FSH and LH which were also analyzed.
Study Type
OBSERVATIONAL
Enrollment
21
Comparison of semen analysis results and sex-related hormone levels between the dependent groups which were defined as before COVID-19 and after COVID-19 (the data of the same patient group were compared as before and after the diagnosis of COVID-19).
Ankara City Hospital
Ankara, Turkey (Türkiye)
Semen analyses parameters including sperm motility (total, progressive, non-progressive and immotile
cell count percentage
Time frame: first 1 hour
Semen analyses parameters including sperm concentration
cell count per milliliters of semen sample.
Time frame: first 1 hour
Semen analyses parameters including sperm morphology
percentage of normal forms
Time frame: first 1 hour
Semen analyses parameters including semen volume
milliliters
Time frame: first 1 hour
Sex-related hormone levels including testosterone
nanograms per deciliter
Time frame: 20 minutes
Sex-related hormone levels including follicle stimulating hormone and luteinizing hormone
Units per liter
Time frame: 20 minutes
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