Purpose: to evaluate the efficacy and safety of erector spinal block (ESB) for analgesia in laparoscopic cholecystectomy（LC）. Method: This study is a randomized, single-blind, controlled clinical trial. Pre-operative ultrasound-guided bilateral erector spinae plane block will be performed in the ESPB group. Vertebral side block will be performed in the VSB group. And the control group will receive local anaesthesia after the surgery. Intraoperative and postoperative analgesia effect and side effects will be compared between the three groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
90
After induction of general anesthesia, pre-operative ultrasound-guided bilateral erector spinae plane block/ vertebral side block will be performed in the ESPB/VSB group. Local block will be performed at the surgical incisions after the surgery under general anesthesia. All the intervention will be performed without patients' awareness.
Pain intensity at rest(Hour 2)
Using the Numeric Rating Scale (NRS) to evaluate the pain intensity at rest two hours after the surgery.
Time frame: Hour 2
Pain intensity at rest (Hour 6)
Using the Numeric Rating Scale (NRS) to evaluate the pain intensity at rest six hours after the surgery.
Time frame: Hour 6
Pain intensity at rest (Hour 24)
Using the Numeric Rating Scale (NRS) to evaluate the pain intensity at rest 24 hours after the surgery.
Time frame: Hour 24
The overall dose of remifentanil
The overall dose of remifentanil used in the surgery.
Time frame: During the surgery
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