The goal of the project: to study the dynamics of the humoral and cellular immunity in patients after pneumonia caused by the SARS-CoV-2 virus at different time intervals, in order to predict the duration of immune protection
* to form study groups of patients (at least 60 patients in total) who have recovered from pneumonia of varying severity caused by the SARS-CoV-2 virus (at least 30 patients in each of the groups of patients who have had pneumonia in moderate and severe forms); * to investigate the parameters of cellular immunity (the content of antigen-specific T-cells to the main viral antigens - proteins S, N, M) in patients of different groups included in the trials, in dynamics 3, 6, 9 and 12 months after the COVID-19-associated pneumonia; * to investigate the indicators of humoral immunity (the content of IgG to the main viral antigens - proteins S, N, M) in patients of different groups included in the trials, in dynamics 3, 6, 9 and 12 months after the COVID-19-associated pneumonia.
Study Type
OBSERVATIONAL
Enrollment
274
Humoral (IgG) and cellular (antigen-specific cells) immunity
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Minsk, Belarus
The dynamics of humoral and cellular immunity
The dynamics of both humoral and cellular immunity in response to COVID-19 infection
Time frame: 1 year
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