Coronary Interventions Ulm - Coronary Chronic Total Occlusions

University Hospital Ulm500 enrolled

Overview

The aim of the proposed project is to provide the long-term results after a recanalization attempt of chronically occluded coronary arteries. To investigate recanalization attempt of chronically occluded coronary arteries at the Ulm University Hospital. As shown, it is known that successful recanalization of a chronic occlusion is associated with a lower event rate (reduced mortality and the need for operative myocardial revascularization) compared to unsuccessful recanalization (drug therapy). The standard in the therapy of successfully recanalized chronic occlusions is the use of drug-releasing vascular supports.

Study Type

OBSERVATIONAL

Enrollment

500

Conditions

Chronic Total Occlusion of Coronary Artery Chronic Total Occlusion

Interventions

PCI - percutaneous coronary interventionPROCEDURE

percutaneous coronary intervention

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients over 18 years Coronary intervention in chronic coronary artery occlusion Occlusion \> 3 months Indication for PTCA or recanalization according to guidlines such as: Symptoms of the patient Evidence of myocardial ischemia (stress ECG, scintigraphic Methods, magnetic resonance imaging, stress echocardiography) pathological intracoronary flow reserve, prognostic Exclusion Criteria: * No chronic occlusion, * Contraindication to anti-platelet therapy Acetylsalicylic acid plus clopidogrel for at least 3 months such as e.g. with florid gastrointestinal ulcer disease, History of hemorrhagic stroke or urgent non-postponable surgical intervention. Basic disease with a life expectancy of less than 12 months (here as a rule no indication for PTCA or reopening available)

Outcomes

Primary Outcomes

MACE

major adverse cardiac event

Time frame: 1 year

Secondary Outcomes

TLR

target lesion revascularization