Shanghai Meiji Health Science and Technology Co., Ltd

Shanghai Meiji Health Science and Technology Co., Ltd.95 enrolled

Overview

Investigators performed a randomized double-blind trial to determine the effects of long-term NnEx ingestion in patients with overweight or obesity. Ninety-five participants (23\<BMI\<30 kg/m2) were randomly allocated to three groups: a control group, a 1 g/day NnEx group, and a 2 g/day NnEx group. The effects of the consumption of 2 g/day or 1 g/day NnEx for 12 weeks on indices of adiposity and fasting blood metabolic parameters were compared with those of no consumption of NnEx.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

DOUBLE

Enrollment

Conditions

Over Weight People

Interventions

Nelumbo nucifera Leaf ExtractDIETARY_SUPPLEMENT

Hot water extracted Nelumbo nucifera Leaf, mainly containing quercetin and quercetin 3-O-glucuronide.

Eligibility

Sex: ALLMin age: 40 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Has a body mass index (BMI) of 23-30 kg/m2 * Has no history of using any antidiabetic medication * Absence of liver, kidney, or heart disease * Absence of food allergy and daily tea consumption \<2 L * Meet all of the above criteria and to follow the instructions given during the study. Exclusion Criteria: * Testing delayed for \>1 week without justification * Difficulty attending the hospital on the required days * Lack of data regarding the times of beverage consumption for over 5% of the study * Abnormal overeating * Test results believed to be unreliable because of the lack of provision of diet and exercise reports during the fasting period * Difficulty drawing blood * Poor confidence in the test data