About 70% of colon cancer patients are anemic. Preoperative anemia in patients with colorectal cancer is associated with both impaired disease-free survival and overall survival. The purpose of this study is to compare the effects of preoperative iv iron substitution on postoperative recovery in preoperatively anemic (male Hb \<130, female Hb \<120) and iron deficient colon cancer patients in a prospective setup. As a primary outcome, the effect of iv-iron substitution on postoperative complications is investigated.
Randomized preoperative iron substitution for patient with iron deficient anemia
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
514
Iron-arm treated with Ferric carboxymaltose, non-iron arm without
Jorvi Hospital
Espoo, HUS, Finland
RECRUITINGpostoperative complications
At study, difference between arms will be evaluated: Complications are analysed using Clavien-Dindo classification https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360123/bin/3TT1.jpg
Time frame: 30 days
Need for red blood cell transfusion
Number of Participants in need for red blood cells transfusion per arm
Time frame: 30 days
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