Clinical Manifestations and Long-Term Outcome in Early Lyme Neuroborreliosis

University Medical Centre Ljubljana311 enrolled

Overview

In this retrospective cohort study of patients with early Lyme neuroborreliosis (LNB), clinical and microbiologic characteristics and long-term outcome of definite vs. possible LNB were evaluated at a single university medical center in Slovenia. Severity of acute disease and long-term outcome during a 12-month follow-up were assessed using a composite clinical score based on objective clinical findings and subjective complaints.

Study Type

OBSERVATIONAL

Enrollment

311

Conditions

Lyme Disease

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * early Lyme neuroborreliosis Exclusion Criteria: * Not fulfilling study criteria for definite or possible Lyme neuroborreliosis * Alternative diagnosis during follow-up * Concomitant tick-borne encephalitis * Clinical symptoms/signs present for \>6 months * Data not available

Locations (1)

University Medical center Ljubljana

Ljubljana, Slovenia

Outcomes

Primary Outcomes

composite clinical score

Composite clinical score based on objective clinical findings and subjective complaints. The sum of subjective complaints and objective findings scored as 0=absent or 1=present represent severity of disease on admission or clinical outcome at follow-up, respectively. Maximum total score=31

Time frame: follow-up for 12 months-post-treatment

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.