BPA Levels Relationship With IVF/ICSI Outcomes in Low Ovarian Reserve

N/ACompletedNCT04654598

Nefise Nazlı YENIGUL74 enrolled

Overview

The relationship between BPA elevation in urine, blood, and follicle fluid and embryo quality, IVF/ICSI outcomes.

Study Type

INTERVENTIONAL

Allocation

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Infertility Low Over Reserve IVF Infertility, Female

Interventions

BPA levelsOTHER

BPA (bisphenol A) in urine, blood and follicle fluid samples

Eligibility

Sex: FEMALEMin age: 25 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * patients who underwent IVF due to low ovarian reserve * patients provided urine, blood, and follicle fluid (FF) samples on the oocyte retrieval day * patients who did not smoke or use alcohol * patients did not work in the plastic industry Exclusion Criteria: * patients who underwent IVF due to unexplained infertility or tubal factor or male factor indications * patients diagnosed with endometriosis * patients with freeze-all cycles * patients having previous ovarian surgery * women with metabolic disease (such as hypertension or diabetes mellitus) * patients with a known genetic problem (male or female)

Locations (1)

Nefise Nazlı YENIGUL

Sanliurfa, Turkey (Türkiye)

Outcomes

Primary Outcomes

Exposure to BPA

Concentrations of Bisphenol A (BPA) will be quantified in the urine, blood plasma, and follicular fluid (individual and pooled samples) by use of ELİSA test in women with low ovarian reserve

Time frame: 6 month

Data from ClinicalTrials.gov

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