Metabolism and Excretion of [14C]CC-90001 in Healthy Male Subjects

Inclusion Criteria: Subjects must satisfy the following criteria to be enrolled in the study: 1. Subject is ≥18 and ≤55 years of age, from any race, at the time of signing the informed consent form (ICF). 2. Subject is a male. 3. Subject must understand and voluntarily sign an ICF prior to any study-related assessments/procedures being conducted. 4. Subject is willing and able to adhere to the study visit schedule and other protocol requirements. 5. Subject is in good health, as determined by the Investigator based on a physical examinations and laboratory testing at screening or at check-in. 6. Must practice true abstinence or agree to use a barrier method of birth control (condoms not made out of natural \[animal\] membrane \[latex condoms are recommended\]) during sexual contact with a pregnant female or female of childbearing potential (FCBP) on the day of taking the single dose of study drug and for at least 90 days after taking the single dose of study drug. This also applies to those subjects who have had a successful vasectomy. 7. Subject has a body mass index (BMI) ≥ 18 and ≤ 33kg/m2 at screening. 8. Subject is afebrile, with supine systolic blood pressure (BP) ≥ 90 and ≤ 160mmHg, supine diastolic BP ≥ 50 and ≤ 100 mmHg, and pulse rate ≥ 40 and ≤ 90bpm at screening and check-in. 9. Subject has screening laboratory test results within the reference range or, if outside the reference range, documented to be not clinically significant by the Investigator. 10. Subject has a normal or clinically acceptable 12-lead electrocardiogram (ECG), with a QT interval corrected using Fredericia formula (QTcF) value ≤ 450 msec, at screening and check-in Exclusion Criteria: 1. Subject has any significant medical condition, laboratory observation, or psychiatric illness that would prevent the subject from participating in the study. 2. Subject has any condition including a laboratory test result which places the subject at unacceptable risk if he were to participate in the study. 3. Subject has any condition that confounds the ability to interpret data from the study. 4. Subject was exposed to an investigational drug (new chemical entity) within 30days prior to dosing, or 5half-lives of that investigational drug, if known (whichever is longer). 5. Subject has used any prescribed systemic or topical medication (including but not limited to analgesics, anesthetics, etc) within 14 days or 5 half-lives of that medication, whichever is longer, prior to dosing. 6. Subject has used any non-prescribed systemic or topical medication (including vitamin/mineral supplements and herbal medicines) within 7days prior to dosing. 7. Subject has used CYP3A inducers and/or inhibitors (including St. John's Wort) within 30days prior to dosing. The Indiana University "Cytochrome P450 Drug Interaction Table" should be utilized to determine inducers and/or inhibitors of CYP3A (http://medicine.iupui.edu/clinpharm/ddis/table.aspx). Please consult the medical monitor for any uncertainties with regard to potential CYP3A modulators. 8. Subject has any surgical or medical conditions possibly affecting drug absorption, distribution, metabolism, and excretion, eg, bariatric procedure or Gilbert's syndrome. a. Note: prior appendectomy is acceptable, but prior cholecystectomy would result in exclusion from the study. Please consult the medical monitor for uncertainties around the relevance of prior surgical procedures. 9. Has donated blood or plasma within 2weeks before dose administration to a blood bank or blood donation center. 10. Subject has a history of drug abuse (as defined by the current version of the Diagnostic and Statistical Manual \[DSM\]) within 2 years prior to dosing, or positive drug test reflecting consumption of drugs of abuse. 11. Subject has a history of alcohol abuse (as defined by the current version of the DSM) within 2 years prior to dosing, or positive alcohol test. 12. Positive SARS-CoV-2 (severe acute respiratory syndrome coronavirus) test or signs/symptoms of COVID-19 (Coronavirus Disease 2019) infection. 13. Subject is known to have serum hepatitis or be a carrier of Hepatitis B virus (HBV) or Hepatitis C virus (HCV); or express hepatitis B surface antigen (HBsAg) or hepatitis C antibody (HCV Ab), or have a positive result to the test for human immunodeficiency virus (HIV) antibodies at screening. 14. Smokers or users of other tobacco products (self-reported). 15. Subject has received immunization with a live or live attenuated vaccine within 1 months prior to dosing or is planning to receive immunization with a live or live attenuated vaccine for 1months following dosing. 16. Subjects who have participated in more than one other radiolabeled investigational drug study within 12 months prior to Check-in (Day-1). a. Note: The previous radiolabeled investigational drug must have been received more than 6 months prior to check-in (Day-1) and the total planned exposure from this current study and the previous study must be within the recommended levels considered safe, per US code of federal regulations (CFR) governing Protection of Human Subjects; radioactive drugs for certain research uses (ie, less than 5000 mrem whole body annual exposure; 21CFR361.1). 17. Subject was exposed to serial X-ray or computed tomography scans, barium meal, or employment in a job requiring radiation exposure monitoring within 12 months prior to Day-1. 18. History of less than 1 to 2 bowel movements per day. 19. Subject is part of the study site personnel or a family member of the study site staff.