This is a non-interventional (observational), retrospective medical record review study collecting data reported in medical records of patients with T2D (Type 2 Diabetes ) who were treated with any basal-insulin or premix-insulin (plus/minus OAD (Oral Antidiabetic Drug)) for at least 26 weeks prior to switching to Ryzodeg® and treated for at least 26 weeks after switching to Ryzodeg® (plus/minus OAD). All patients have been treated at the discretion of the treating physician in accordance with the Ryzodeg® label in South Korea.
Study Type
OBSERVATIONAL
Enrollment
200
All patients have been treated at the discretion of the treating physician in accordance with the Ryzodeg® label in South Korea. Hence independently of this study, the treating physician has determined the starting dose of Ryzodeg® as well as any dose adjustments thereafter.
Novo Nordisk Investigational Site
Daejeon, South Korea
Novo Nordisk Investigational Site
Daejeon, South Korea
Novo Nordisk Investigational Site
Seongnam-si, South Korea
Novo Nordisk Investigational Site
Seoul, South Korea
Novo Nordisk Investigational Site
Seoul, South Korea
Novo Nordisk Investigational Site
Suwon-si, Gyeonggi-do, South Korea
Change in HbA1c (Glycosylated Hemoglobin)
Percentage point
Time frame: Period 1 (week -26 to week 0), Period 2 (week 0 to week 26)
Patients with HbA1c less than 7.0 percentage (Yes or No)
Percentage of patients
Time frame: At baseline (week 0)
Patients with HbA1c less than 7.0 percentage (Yes or No)
Percentage of patients
Time frame: End of study (week 26)
Patients with HbA1c less than 7 percentage without any hypoglycaemic events during the previous 26 weeks (Yes or No)
Percentage of patients
Time frame: At baseline (week 0)
Patients with HbA1c less than 7 percentage without any hypoglycaemic events during the previous 26 weeks (Yes or No)
Percentage of patients
Time frame: End of study (week 26)
Difference in the number of overall hypoglycaemia events within 26 weeks before and after the switch to Ryzodeg®
Number of events
Time frame: Period 1(week-26 to week 0), Period 2(week 0 to week 26)
Difference in the number of severe hypoglycaemia events within 26 weeks before and after the switch to Ryzodeg®
Number of events
Time frame: Period 1(week-26 to week 0), Period 2(week 0 to week 26)
Change in FPG (Fasting Plasma Glucose)
mmol/L
Time frame: Period 1 (week -26 to week 0), Period 2 (week 0 to week 26)
Change in daily total insulin dose
Unit/day
Time frame: Period 1 (week -26 to week 0), Period 2 (week 0 to week 26)
Change in daily basal insulin dose
Unit/day
Time frame: Period 1 (week -26 to week 0), Period 2 (week 0 to week 26)
Change in daily prandial insulin dose
Unit/day
Time frame: Period 1 (week -26 to week 0), Period 2 (week 0 to week 26)
Change in body weight
Kg
Time frame: Period 1 (week -26 to week 0), Period 2 (week 0 to week 26)
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