Remote Ischemic Conditioning for the Treatment of Intracerebral Hemorrhage

Inclusion Criteria: 1. Age ≥ 18 and ≤ 80 years 2. The diagnosis of supratentorial ICH is confirmed by brain CT scan 3. Hematoma volume of 10 to 30 ml and Glasgow Coma Score (GCS)\>8 at randomization. 4. National Institutes of Health Stroke Scale (NIHSS)≥6 and ≤20 points at randomization. 5. Randomization and starting treatment between 24 and 48 hours of symptom ictus. 6. Signed and dated informed consent is obtained. Exclusion Criteria: 1. Planned surgical evacuation of ICH prior to administration of investigational intervention 2. ICH concomitant with subarachnoid hemorrhage or intraventricular hemorrhage 3. Suspected secondary ICH related to tumor, ruptured aneurysm or arteriovenous malformation, hemorrhagic transformation of an ischemic infarct, or venous sinus thrombosis 4. Patients with a pre-existing neurological deficit (mRS\>1) or psychiatric disease that would confound the neurological or functional evaluations. 5. Coagulopathy - defined as elevated aPTT or INR \>1.3 upon presentation; concurrent use of direct thrombin inhibitors (such as dabigatran), direct factor Xa inhibitors (such as rivaroxaban or apixaban), or low-molecular-weight heparin 6. Severe renal disease (i.e., renal disorder requiring dialysis ) or eGFR \<30ml/min/1.73m2 7. Severe liver disorder, or ALT \>3 times or bilirubin \>2 times upper limit of normal 8. Known severe hearing loss or cognitive impairment 9. Known pregnancy, or positive pregnancy test, or breastfeeding 10. Patients known or suspected of not being able to comply with the study protocol due to alcoholism, noncompliance or any other cause 11. Life expectancy of less than 90 days due to co-morbid conditions 12. Concurrent participation in another research protocol for investigation of another experimental therapy 13. Severe, sustained hypertension (Systolic blood pressure\> 180 mmHg or diastolic blood pressure\> 110 mmHg). 14. Contraindication for remote ischemic conditioning: severe soft tissue injury, fracture, or peripheral vascular disease in the upper limbs. 15. Any condition which, in the judgement of the investigator, might increase the risk to the patient.