ACOART RF CLOSURE:Radiofrequency for Varicose Veins of Lower Extremity in China

Inclusion Criteria: * 18 to 80 years of age * Patients clinically diagnosed as primary varicose great saphenous veins of lower extremity. And unilateral superficial varicose veins of lower extremity will be treated in this procedure. * Patients with CEAP classification as C2-C5. * Voluntarily participate in this study and sign the informed consent form Exclusion Criteria: * patients with target vein diameter \< 2mm or \> 15mm. * the distance between the anterior wall of the vessel and the skin of the target vein under ultrasound is less than 0.5cm. * patients with aneurysmal dilation at the saphenous femoral junction. * patients with venous aneurysm (defined as venous hemangioma with a diameter greater than or equal to 2 times the diameter of the adjacent vein). * thrombosis or thrombophlebitis in the trunk of great saphenous vein. * the great saphenous vein is so tortuous that radiofrequency closure catheter cannot cross the vein trunk. * patients with target diseased vessels who have received surgical treatment in the past. * patients with deep venous thrombosis or a history of pulmonary embolism. * patients with active implants such as pacemakers or ICD. * patients with severe hepatic and renal dysfunction (ALT \> normal upper limit 3 times; creatinine \> 225umol/L). * patients who are contraindications to anesthesia. * patients with secondary varicose veins caused by deep venous thrombosis syndrome, Cockett syndrome (iliac vein compression syndrome), KT syndrome (venous malformation hypertrophy syndrome), arteriovenous fistula, etc. * any serious or uncontrollable systemic disease (including uncontrolled hypertension, diabetes, active bleeding signs or severe coagulation disorders, etc.). * patients with diseases that may cause difficulties in treatment and evaluation (such as malignant tumors, acute infectious diseases, septicemia, general intolerability of surgery, life expectancy less than 12 months, etc.). * pregnant and lactating women, or those who had a planned birth during the study period. * patients who have participated in clinical trials of other drugs or medical devices in the past 3 months. * According to the judgement of the investigator, other situations that are not suitable for enrollment.