Study on the Correlation Between Gene Mutation and TCM Syndrome Types in Metastatic Colorectal Cancer

Inclusion Criteria: 1. A clear pathological diagnosis is a patient with colorectal cancer; 2. Have complete TNM staging information; 3. There is a clear diagnosis of the location and time of metastasis; 4. Age ≥18 years old, ≤80 years old, male or female; 5. There is a clear time for the first treatment with Chinese medicine; 6. Patients who can receive long-term follow-up. - Exclusion Criteria: 1. Patients with colorectal cancer diagnosed pathologically as adenosquamous carcinoma, squamous cell carcinoma, carcinoid, small cell carcinoma, malignant lymphoma, etc.; 2. Patients with double cancer, multiple or metastatic colorectal cancer; 3. Combined with severe acute and chronic diseases that may affect treatment and prognosis, such as myocardial infarction, stroke, severe renal insufficiency and mental illness;-