Influence of Two Paraffin Wax Chewing Gums of Different Consistency on the Stimulated Saliva Flow Rate

University Hospital, Basel, Switzerland81 enrolled

Overview

The study examines two different chewing gums with regard to consistency and its influence on the result of sialometry

The examination (sialometry) is performed on healthy volunteers. The volunteers must chew on a paraffin gum for seven minutes. After each minute, the amount of secreted saliva is spat into a designated cup and evaluated. This test is performed with Aurosan chewing gum and later with GC Europe chewing gum.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Xerostomia

Interventions

Paraffin Pellets from Aurosan GmbHDIAGNOSTIC_TEST

1 to 2 minutes pre-chewing time chewing Paraffin Pellets from Aurosan GmbH, after which the amount of saliva is collected over a period of five minutes. The patient may chew the chewing gum once per second; after each minute the produced amount of saliva is spit in a cup, the whole amount measured after 5 minutes.

Chewing wax from the Saliva-Check Buffer from GC EuropeDIAGNOSTIC_TEST

1 to 2 minutes pre-chewing time chewing wax from the Saliva-Check Buffer from GC Europe, after which the amount of saliva is collected over a period of five minutes. The patient may chew the chewing gum once per second; after each minute the produced amount of saliva is spit in a cup, the whole amount measured after 5 minutes.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy volunteers * non-smoker * no medication Exclusion Criteria: * physical or mental illnesses * smokers * regular medication intake * pregnant women * dementia or persons who are unable to judge or persons with guardianship * minor test persons

Locations (1)

University Center for Dentistry Basel UZB

Basel, Canton of Basel-City, Switzerland

Outcomes

Primary Outcomes

Stimulated salivary flow rate (ml)

Comparing measurements of stimulated salivary flow rate (ml) after chewing two different chewing gums

Time frame: at baseline (approx 40 minutes)

Secondary Outcomes

Change in consistency of chewing gum

Change in consistency (compressive strength, measured in Newton) of the chewing gums for stimulated salivary flow rate measurement over a time period of 7 minutes chewing time

Time frame: at baseline (7 minutes for each chewing gum)

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.