Crohn's disease and Ulcerative colitis are chronic disease that are usually diagnosed at young age. The diseases and the associated treatment can impact on patient's sexual function, fertility, pregnancy, and delivery. This study aims to assess the impact of inflammatory bowel diseases on these aspects in female patients.
This is a cross-sectional, international, multicentre study. Female patients diagnosed with inflammatory bowel diseases (Crohn's disease and ulcerative colitis) treated at several Italian centres will be retrospectively assessed for inclusion. Those who underwent surgery below the age of 35 years between 2000 and 2020 will be included. The study aims to obtain information on female fertility, pregnancy and delivery, and to identify factors associated with infertility and problems to conclude the pregnancy. For each nation, at least one centre will collect data on patients who were not treated with surgery. Patients who meet inclusion criteria will be asked to prospectively fill a questionnaire on fertility and pregnancy. Data on treatments and demographic will be retrospectively collected by the local investigators and uploaded on a secure online database.
Study Type
OBSERVATIONAL
Enrollment
500
Any surgical procedures performed for inflammatory bowel diseases
Any treatment (including non-surgical) performed for inflammatory bowel diseases
Policlinico S.Orsola-Malpighi
Bologna, Italy
RECRUITINGRho Memorial Hospital
Milan, Italy
NOT_YET_RECRUITINGUniversitá degli Studi della Campania Luigi Vanvitelli
Napoli, Italy
NOT_YET_RECRUITINGPoliclinico Tor Vergata
Roma, Italy
RECRUITINGFertility
Rate of infertility and number of pregnancies. Number of attempts to achieve pregnancy.
Time frame: through study completion, an average of 1 year
Pregnancy
Rate of successful pregnancies. Number of miscarriages.
Time frame: through study completion, an average of 1 year
In-vitro fertilization
Number of in-vitro fertilization attempts
Time frame: through study completion, an average of 1 year
Abortion/s
Number of abortions and reasons.
Time frame: through study completion, an average of 1 year
Complications, surgical
Incidence of early and late surgical complications and effects on fertility
Time frame: through study completion, an average of 1 year
Complications, medical
Incidence of medical complications and effects on fertility
Time frame: through study completion, an average of 1 year
Surgical approach
Rate of minimally invasive surgery use and effect on fertility and pregnancy
Time frame: through study completion, an average of 1 year
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