The Characteristics and Role of Mucosal Microbiome After Treatment of Clostridioides Difficile Infection

Inclusion Criteria: * Adults aged 18 and over * No history of C. difficile infection * Undergoing clinically indicated colonoscopy for colon cancer screening or colon polyp surveillance purposes in the absence of active GI symptoms. Exclusion Criteria: * Known active pregnancy * Other known active gastrointestinal infectious process * Inflammatory gastrointestinal conditions (microscopic colitis, inflammatory bowel disease, Celiac disease) * Vulnerable adults * Any other disease(s), condition(s) or habit(s) that would interfere with completion of study, or in the judgment of the investigator would potentially interfere with compliance to this study or would adversely affect study outcomes