While absolute quantification in 18F-FDG PET (Positon Emission Tomography) is widely used in clinical routine, absolute quantification in SPECT (Single Photon Emission Computed Tomography) is under development and its clinical interest remains to be demonstrated. Recent studies carried out on bone scan recordings show the potential interest of quantification indexes such as SUV (Standard Uptake Value).
In oncology, bone scan studies have reported significantly higher SUV values for secondary bone lesions compared with benign osteoarticular lesions , and some have even defined an SUVmax threshold value that points to prostatic bone metastases.
Study Type
OBSERVATIONAL
Enrollment
21
SPECT/CT scan of the spine as part of a vertebroplasty
CHU de Nancy - Hôpital Brabois
Vandœuvre-lès-Nancy, France
Chru Nancy
Vandœuvre-lès-Nancy, France
CHRU of Nancy
Vandœuvre-lès-Nancy, France
To validate the absolute bone scan quantification in a retrospectively selected patient population
Analysis of SUV variation on at least 2 bone scans: Variation of the SUV over time on scans of patients with spinal fractures
Time frame: After 1 year
To calibrate the tomographic images from the gamma camera
Calibrate the tomographic images from the gamma camera to obtain a volume activity in Bq/mLand densities
Time frame: 1 day
To evaluate the attenuation correction on phantoms of different density
SUV absolute quantitation index (SUVmax, SUVpeak, SUVmean).
Time frame: 1 day
To evaluate absolute quantification on phantoms
Evaluate absolute quantification on phantoms with objects of different volumes
Time frame: 1 day
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